Friday, 22nd March 2019

Artificial intelligence predicts treatment effectiveness

How can a doctor predict the treatment outcome of an individual patient? Traditionally, the effectiveness of medical treatments is studied by randomised trials where patients are randomly divided into two groups: one of the groups is given treatment, and the other a placebo. Is this really the only reliable way to evaluate treatment effectiveness, or could something be done differently? How can the effectiveness of a treatment method be evaluated in practice? Could some patients benefit from a treatment that does not cause a response in others?

A new method developed by Finnish researchers at the University of Eastern Finland, Kuopio University Hospital and Aalto University now provides answers to these questions. Using modelling, the method makes it possible to compare different treatment alternatives and to identify patients who will benefit from treatment. Relying on artificial intelligence, the method is based on causal Bayesian networks.

According to Professor Emeritus Olli-Pekka Ryynänen from the University of Eastern Finland, the method opens up new and significant avenues for the development of medical research. “We can now predict the treatment outcome in individual patients and to evaluate existing and new treatment methods. With this method, it is also possible to replace some randomised trials with modelling,” Professor Emeritus Ryynänen says.

In the newly published study, the researchers used the method to evaluate treatment effectiveness in obstructive sleep apnoea; however, the method can also be applied to other treatments. The study showed that in patients with sleep apnoea, the continuous positive airway pressure (CPAP) treatment reduced mortality and the occurrence of myocardial infarctions and cerebrovascular insults by five percent in the long term. For patients with heart conditions, CPAP was less beneficial.

The findings were reported in Healthcare Informatics Research.

By 2030, 80 per cent of the work of today’s project management (PM) discipline will be eliminated as...
Organisations will need to overcome challenges to scale the technology.
Focus is on accelerating drug discovery in oncology and autoimmunity.
Personalised AI assistants, robotic process automation and face recognition for attendance marking....
Global packaging manufacturer uses the Cognito® platform from Vectra to expose hidden attackers and...
Collaboration speeds up critical functions such as image recognition and inferencing at the edge.
Natural language processing coupled with predictive analytics serve as key drivers to meaningful cus...
Commitment includes new advanced AI technologies and solutions & AI Accelerator Programme offering s...